Föreläsningar och seminarier StratRegen Seminarieserie med Maria Barna
Välkommen till ett ny seminarium i StratRegen Lunch Seminarie Serien på onsdag, den 24:de of April 2024 12.00-13.00 i Biomedicum, Campus Solna.
Title: Ribosomes in Gene Regulation: Controlling the diversity of proteins made in specific cells, tissues and organisms
Speaker: Maria Barna, Associate Professor in the Department of Genetics at Stanford University
Barna lab web site: https://barnalab.stanford.edu/
Evolutionarily divergent mTOR remodels translatome for tissue regeneration.
Zhulyn O, Rosenblatt HD, Shokat L, Dai S, Kuzuoglu-Öztürk D, Zhang Z, Ruggero D, Shokat KM, Barna M
Nature 2023 Aug;620(7972):163-171
A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production.
Genuth NR, Shi Z, Kunimoto K, Hung V, Xu AF, Kerr CH, Tiu GC, Oses-Prieto JA, Salomon-Shulman REA, Axelrod JD, Burlingame AL, Loh KM, Barna M
Nat Commun 2022 Sep;13(1):5491
Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics.
Leppek K, Byeon GW, Kladwang W, Wayment-Steele HK, Kerr CH, Xu AF, Kim DS, Topkar VV, Choe C, Rothschild D, Tiu GC, Wellington-Oguri R, Fujii K, Sharma E, Watkins AM, Nicol JJ, Romano J, Tunguz B, Diaz F, Cai H, Guo P, Wu J, Meng F, Shi S, Participants E, Dormitzer PR, Solórzano A, Barna M, Das R
Nat Commun 2022 Mar;13(1):1536
Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c.
Fujii K, Zhulyn O, Byeon GW, Genuth NR, Kerr CH, Walsh EM, Barna M
Dev Cell 2021 Nov;56(21):2928-2937.e9
Gene- and Species-Specific Hox mRNA Translation by Ribosome Expansion Segments.
Leppek K, Fujii K, Quade N, Susanto TT, Boehringer D, Lenarčič T, Xue S, Genuth NR, Ban N, Barna M
Mol Cell 2020 Dec;80(6):980-995.e13
The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity.
Simsek D, Tiu GC, Flynn RA, Byeon GW, Leppek K, Xu AF, Chang HY, Barna M
Cell 2017 Jun;169(6):1051-1065.e18
RNA regulons in Hox 5' UTRs confer ribosome specificity to gene regulation.
Xue S, Tian S, Fujii K, Kladwang W, Das R, Barna M
Nature 2015 Jan;517(7532):33-8
Sandwiches and coffee will be provided.
Host
Enric Llorens Bobadilla
Biträdande LektorElif Eroglu
ForskareStratRegen supports researchers, research programs and infrastructure at the Karolinska Institutet (KI) within the field of stem cells and regenerative medicine based on scope, quality, and the potential to strengthen and develop the field.