Föreläsningar och seminarier Pediatric Oncology seminar
Speaker: Tatiana von Bahr Greenwood, pediatric oncologist (MD/PhD), Jan-Inge Henter Group
Title: Screening with neurofilament light (NFL) in plasma for neurodegeneration in LCH, and implementation in the clinic
Summary: NFL in cerebrospinal fluid (CSF) is a relevant surrogate biomarker for neurodegeneration in CNS-LCH. However, lumbar puncture is an invasive procedure. In a recent study, our results suggest that NFL in plasma may be used as screening for ND-CNS-LCH, where elevated values are confirmed with NFL in CSF. We recommend NFL in plasma to be implemented in clinical practice at our clinic.
Moderator: Désirée Gavhed