Föreläsningar och seminarier OnkPat Friday Seminar: Engineering exosomes for delivery of genome editors and RNA therapeutics
Välkommen till OnkPat Friday Seminar med Samir El Andaloussi, professor vid institutionen för laboratoriemedicin, Karolinska Institutet.
Värd: Kasper Karlsson, institutionen för onkologi-patologi
Läs mer om Samir El Andaloussi på den engelska sidan.
Utvalda publikationer
Efficient genome editing in the non-human primate brain using programmable extracellular vesicles
Liang, X., Zhou, H., Nizamudeen, Z. A., Kyriakopoulou, E., Evans, A. E., Roudi, S., Estupiñán, H. Y., Rädler, J., Hou, V. W. Q., Daniel, C. D.W., Hernandez-Perez, I., Singh, M., Parsi, P., Lonergan, D. A., Berlana, L. M., Walmsley, R., Chen, Y., Suermondt, J. S. M. T., Mowoe, M. O., Görgens, A., Smith, C. A., Redrup, G. O., Ashmore, L. D., Perez, S., Thapa, K. J., Banerjee, S., Bonner, S. E., Conceicao, M., Gavin, R. L., Hean, J., Horrocks, P. D., Levitin, M. O., Lundin, P., Sharma, H., Tawar, R. G., Liu, L., Gupta, D., Carter, D. R. F., Nordin, J. Z. and EL Andaloussi, S. . bioRxiv, 2026. 2026.08.05.741964. doi: 10.64898/2026.08.05.741964.
Engineering of extracellular vesicles for efficient intracellular delivery of multimodal therapeutics including genome editors.
Liang X, Gupta D, Xie J, Van Wonterghem E, Van Hoecke L, Hean J, Niu Z, Ghaeidamini M, Wiklander OPB, Zheng W, Wiklander RJ, He R, Mamand DR, Bost J, Zhou G, Zhou H, Roudi S, Estupiñán HY, Rädler J, Zickler AM, Görgens A, Hou VWQ, Slovak R, Hagey DW, de Jong OG, Uy AG, Zong Y, Mäger I, Perez CM, Roberts TC, Carter D, Vader P, Esbjörner EK, de Fougerolles A, Wood MJA, Vandenbroucke RE, Nordin JZ, El Andaloussi S
Nat Commun 2025 Apr;16(1):4028
Antibody-displaying extracellular vesicles for targeted cancer therapy.
Wiklander OPB, Mamand DR, Mohammad DK, Zheng W, Jawad Wiklander R, Sych T, Zickler AM, Liang X, Sharma H, Lavado A, Bost J, Roudi S, Corso G, Lennaárd AJ, Abedi-Valugerdi M, Mäger I, Alici E, Sezgin E, Nordin JZ, Gupta D, Görgens A, El Andaloussi S
Nat Biomed Eng 2024 Nov;8(11):1453-1468
Novel Endogenous Engineering Platform for Robust Loading and Delivery of Functional mRNA by Extracellular Vesicles.
Zickler AM, Liang X, Gupta D, Mamand DR, De Luca M, Corso G, Errichelli L, Hean J, Sen T, Elsharkasy OM, Kamei N, Niu Z, Zhou G, Zhou H, Roudi S, Wiklander OPB, Görgens A, Nordin JZ, Castilla-Llorente V, El Andaloussi S
Adv Sci (Weinh) 2024 Nov;11(42):e2407619