Föreläsningar och seminarier Neurosessions: "Large-scale neuronal recordings: advances and challenges in analysis methodology"

2020-02-07 9:00 Add to iCal
Campus Solna Room D1012, Biomedicum, floor 10, Solnavägen 9, Solna

Heldagsseminarium för doktorander och postdocs följt av diskussion med föreläsarna, med start kl. 09:00 i D1012 i Biomedicum, Solna. Välkomna.


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In recent years, the development of novel recording techniques (wide field calcium imaging and Neuropixels electrophysiological recordings) has enabled multi neuronal recordings, at single cell resolution, in a behaving animal. The methodological advances allow researchers to collect large-scale neuronal activity recordings of an increasing quantity and complexity. 

The complexity of the neuronal data collected, and the analysis that follows, has generated the need to improve our critical thinking towards our own analysis methods. This, in order to extract a deeper understanding of the network activity from the increasing level of complexity discovered in the data collected. Following the acceleration of data acquisition is the advances in the methodology for analyzing neuronal time series data, signal processing and network analysis. Additionally, methods previously used in statistics and machine learning, such as dimensionality reduction and pattern-searching algorithms are also being applied, all seeking to extract an understanding from this high dimensional space of neuronal data complexity. 

Furthermore, different neuroscientific technologies, i.e. calcium imaging and extracellular recordings, have different sensitivity and spatiotemporal scales, resulting in an increasing heterogeneity across studies. The increasing rate of data complexity requires an interdisciplinary effort to develop novel scientific questions, analysis methods and experimental designs that can give way to new innovative theoretical frameworks. 

The aim of this first Neurosession is to incite a discussion centered on these issues with the invited worldwide specialists on calcium imaging, extracellular recordings and computer and statistical science. We believe the topic of this seminar will be of interest for a broad array of PhD students, postdocs and anybody dealing with large datasets of neuronal activity.



Pierre Le Merre Postdoktor