Föreläsningar och seminarier Lecture: Alexander Bershadsky

2019-05-13 13:00 Add to iCal
Karolinska Universitetssjukhuset, Solna J3:14 Kerstin Hagenfeldt, BioClinicum, Solnavägen 30

Prof Bershadsky’s research interests include the mechanisms of cell motility and intracellular traffic, cytoskeleton dynamics, and the crosstalk between cytoskeleton and cell adhesion. The studies from Bershadsky’s laboratory were among the first in which the phenomenon of adhesion-dependent mechanosensitivity was discovered and demonstrated. These studies showed that focal adhesions function as miniature mechanosensors, because their assembly depends on the application of external or cell-generated pulling forces. The aim of the present studies is to clarify the mechanisms involved in the adhesion dependent mechanosensitivity. Other studies from Bershadsky’s lab address the functions of microtubules in the regulation of cell motility and adhesion. His sphere of interest includes the proteins formins as potent regulators of actin assembly and actin-microtubule crosstalk.