Halvtidsseminarier Halvtidskontroll Gina Griffioen

2021-06-10 9:00 Add to iCal
Karolinska Universitetssjukhuset, Solna Sjögren, Psykiatrisektionen, R5:02 & via Zoom

Titel: Molecular imaging investigating neurobiological hypotheses of autism with positron emission tomography (PET)


PhD Jacqueline Borg, Insitutionen för Klinisk neurovetenskap, Karolinska Institutet 

Professor Simon Cervenka, Insitutionen för Klinisk neurovetenskap, Karolinska Institutet 

Professor/psykolog Sven Bölte, Institutionen för Kvinnor och Barns hälsa, Karolinska Institutet  


Assisterande professor Sebastian Lundström, Sektionen för psykiatri och neurokemi, Göteborgs Universitet

Professor Tomas Furmark, Institutionen för psykologi, Uppsala Universitet

Docent Rochellys Diaz Heijtz, Institutionen för Neurovetenskap, Karolinska Institutet 

Kort beskrivning 

Autism Spectrum Disorder (ASD) is life-long disorder with poorly understood neurobiology. ASD is related to alterations in brain development. The process of synapse formation and elimination is likely disturbed, probably causing a different organization of the brain and its circuits. Many processes are involved, and several mechanisms are identified for ASD, where changes in the excitatory/inhibitory balance and alterations in the serotonin system are two of these mechanisms. This thesis will try to contribute to a better understanding of the biological mechanisms behind ASD, by neuro-imaging synapse-density, the excitatory glutamate 5 receptor and parts of the serotonin system. We will also try to study ASD behaviour phenotypes in relation to these potential biomarkers. Lastly, we will try to address replication issues by using Bayesian statistics. 


Gina Griffioen Doktorand