Föreläsningar och seminarier Föreläsning med Sébastien Talbot: "Pain neurons control cancer immunosurveillance"
Välkommen till en föreläsning med Sébastien Talbot "Pain neurons control cancer immunosurveillance", kl. 09:30 i Biomedicum 2 (D0351), OBS! ny tid och plats.
"Pain neurons control cancer immunosurveillance"
Sébastien Talbot, Tier-2 Canada Research Chair in Neuro-Immunology, Assistant Professor. Dept of Pharmacology and Physiology, Université de Montréal, Canada
Under the mentorship of Dr Rejean Couture, Dr Talbot obtained his PhD in Physiology from the Université de Montreal (2012). His thesis focused on the role of CNS immune cells in priming diabetic pain neuropathy. Next, he joined Dr. Clifford Woolf’s lab at the Neurobiology center of Harvard Medical School to study the crosstalk between pain neurons and adaptive immune cells in the context of allergic inflammation.
Since 2017, Dr Talbot joined the UdeM pharmacology and physiology department to start his independent work. His group combines techniques of molecular and cell biology, optogenetics, tissue clearance and imaging, electrophysiology, neuroanatomy, behavior, and genetics. They aim at defining a framework of the neuro-immune interplay at the system level, to decipher how and which sub-population of sensory neurons controls innate and adaptive responses, and to develop new targeted therapies for resolution of chronic inflammatory diseases.
His work is supported by a CFI, CRC-2, CIHR, NSERC and Brain Canada. Specifically, our investigation focus on the role of nociceptor neurons in the control of cancer immunosurveillance. Our hope is that by blocking tumor innervating neurons, we will safeguard the host immune system anti-tumor immunity.